We can liken our body to a very complex machine designed to function at its best. Our organs, hormones and DNA also act like cogs in this machine. What is methylation When we say that, we can liken it to a biological systemic cycle. methylation cycle It is just like a mechanism that allows gears to turn and turns biological switches on and off for a series of processes in the body. After this short analogy, we would like to touch on the actual definition of methylation in the literature and how important it is for our health.
What is Methylation?
Methylation is the chemical reaction of a methyl group. This reaction is an important condition that has the ability to change gene expression. In fact, in the CRP region of the gene that will affect the gene expression. methyl occurs by the reaction of the group. Optimum methylation when it occurs cardiovascular, neurological, reproductive ve detoxification The activity of the systems is also functioning properly. Therefore, a healthy methylation cycle directly affects our systems below. affects:
- DNA production
- Neurotransmitter production
- Histamine metabolism
- Estrogen metabolism
- Eye health
- fat metabolism
- cellular energy
- Liver health
Why is DNA Methylation Important?
To maintain our vitality, to protect our genetic information in a healthy way and to carry this information. DNA it has a big role. Because it takes place in almost all cells in the human body. In addition, deoxyribonucleic acid is composed of carbon, hydrogen, oxygen, nitrogen and phosphorus atoms. In addition, these chains in every cell of the body are mobile and the codes they carry are copied by the mRNA molecule and protein is synthesized.
regeneration of tissues during methylation cycle consists of. This methylation event occurs when the hydrogen atom is replaced by a methyl group. However, if we talk about the importance of the reaction, it is related to gene expression. protein ve DNA metabolism effective in its regulation. As a result DNA methylation If a problem occurs during pregnancy, the problem has the power to reveal an important health problem such as cancer.
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Causes of Methylation Disorder
When the methylation cycle is disrupted, some disruptions occur in body functioning. İinsulin resistance, inflammation, disruption of thyroid functions, vitamin and mineral deficiencies and hormone disorders are among the causes of methylation disorders. Our body, which is affected by methylation disorder, becomes unable to produce the following efficiently after a while:
- Coenzyme Q10
- Nitric oxide
How to Fix Methylation Disorder?
Even if you have a genetic mutation that slows the methylation cycle, increase methylation necessary for the food we consume. vitamins and mineralswe can get. Also, enough food vitamin intake If you can't, you can use additional food supplements, vitamin pills and minerals (supplements) under the supervision of a doctor.
- Vitamin B12 (Offals, eggs, fish, etc.)
- Folic Acid (Beet, cauliflower, broccoli, etc.)
- Vitamin D
- Magnesium (Green leafy vegetables, seafood, etc.)
- Zinc (Garlic, spinach, liver, etc.)
- Vitamin B6 (Legumes - chickpeas-, banana, avocado, etc.)
- Selenium (Walnuts, fish, eggs, etc.)
- Vitamin A (Liver, fish oil, milk, butter, Spinach, parsley, lentils, chard, zucchini, carrots, potatoes, melons, red peppers, etc.).
- Vitamin E (Olive oil, hazelnut oil, almond etc.)
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Last updated October 13, 2021